ជំងឺឆ្កែឆ្កួត Rabies (មានVideos)

Rabies (ជំងឺឆ្កែឆ្កួត) ជំងឺមួយ

នេះគឺកាចសាហាវណាស់ 

អាចឆក់យកអាយុជីវិតមនុស្ស

យើងបានយ៉ាងងាយក្នុងរយះ

ពេលដ៍ខ្លី។ តែជំងឺនេះ 

យើងអាចការពារទុកជាមុនបាន

 ដើម្បីជៀសវាង តំណាក់

កាលហួសពេល។ ពេលឆ្កែខាំ ឬ



 សត្វដែលមានចង្កួមខាំ ជំងឺនេះ និង ឆ្លងតាមទឹក

មាត់ របស់សត្វនោះ មកតាមកន្លែងរបួស រួចមេរោគ Rabies នេះ និង

 បន្តធ្វើដំណើរតាម ប្រពន័្ឋ សរសៃ ឆ្អឹងខ្នង ឡើងទៅកាន់ ខួរក្បាល 

របស់អ្នកជំងឺ....ធ្វើយ៉ាងណា ត្រូវប្រញ៉ាប់ ចាក់ថ្នាំការពារ មុនពេល

 វាឈានទៅដល់ ខួរក្បាល.....មេរោគ Rabies ត្រូវការ រយះពេល ៥


 ទៅ ១០ ថ្ងៃ ដើម្បីឆក់យកជីវិតអ្នកជំងឺ។ 

Deadly Animals Among Us


Rabies

• Viral disease - cause acute encephalitis (inflammation of the brain) in warm-blooded animals.
• Zoonotic (animals to humans).
• Bite from an infected animal
• For a human, rabies is almost invariably fatal if post-exposure prophylaxis is not administered prior to the onset of severe symptoms.
• Virus infect the CNS, cause disease in the brain & death.
• Causative Organism - Lyssavirus genus(Family Rhabdoviridae)

Virus Lifestyle

• Virus replicated in muscle cells near site of bite for most of incubation time.  -Incubation time 30-90days.
• Then ascends along motor and sensory axons at rate of 12-100 mm per day and has predilection for brainstem and medulla
• Enters salivary glands after replication in CNS.

Animal Behavior

• Classic Picture of Rabid, mangy dog foaming at the mouth..not often seen, signs frequently more subtle. 

• Animals - display aggressive behavior, ataxia, irritability, anorexia, lethargy/excessive salivation.

• Cats are more likely to be aggressive than dogs

• Animals exhibit change in instinctive behavior: nocturnal animal walking around in daylight (example. Raccoons)

• Unprovoked bites

Transmission

• Almost all transmission is by bite
• 50 times greater risk than a scratch
• One human case may have been acquired in a laboratory transmitted by aerosol
• In wild animals: Rabies can be transmitted transplacentally
• Transplants in human-possible
• Human-to-human: Never has been confirmed
• Rabies virus never isolated from blood

Encephalitic Form

• Hydrophobia: Patient can't swallow because violent jerky contraction of diaphragm and accessory muscles of inspiration when pt attempts to swallow liquids.  -Patients will be terrified during this reaction and may even experience this at the sight of water or if water touches their face.

• Aerophobia: an extreme fear of air in motion can be elicited from some patients.  This can also cause violent muscles spasms in the neck and pharynx.
• Hallucination, seizures, ataxia, focal weakness and arrhythmias can occur.

Rabies Vaccine

PRINCIPLE: 

Potency of rabies vaccine is determined by comparing a Lethal intra-cerebral dose of a rabies virus with the dose of the standard preparation of rabies vaccines necessary to give for protection.